Diagnosing Environmental Allergies: Comparison of Skin-Prick, Intradermal, and Serum Specific Immunoglobulin E Testing

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Diagnosing environmental allergies: Comparison of skin-prick, intradermal, and serum specific immunoglobulin E testing

BACKGROUND Allergists commonly perform intradermal skin testing (IDST) after negative skin-prick testing (SPT) to comprehensively diagnose environmental allergic sensitization. However, with the availability of modern methods to detect serum-specific immunoglobulin E (ssIgE), it is unclear if ssIgE testing could substitute for IDST. OBJECTIVE To determine the efficacy of ssIgE testing and IDS...

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Reactions to prick and intradermal skin tests.

BACKGROUND Allergy skin testing is a common procedure for the diagnosis of atopic diseases with a small risk of systemic reactions. OBJECTIVE To determine the 12-month incidence of systemic reactions (SRs) to skin prick testing (SPT) and intradermal skin testing (ST) and the symptoms and response to immediate treatment with epinephrine intramuscularly. METHODS A prospective study was conduc...

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Use of intradermal dilutional testing and skin prick testing: clinical relevance and cost efficiency.

OBJECTIVES/HYPOTHESIS The objective was to determine the agreement of the positive results from a multiple skin prick test (SPT) device with the ability to determine a definable endpoint through intradermal dilutional testing (IDT) to compare semiquantitatively the degree of positivity of SPT results with quantitative results from IDT and to analyze the cost of immunotherapy based on SPT compar...

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Use of the skin prick test and specific immunoglobulin E for the diagnosis of cockroach allergy.

OBJECTIVE To compare the prevalence of allergy to cockroaches (Blattella germanica and Periplaneta americana) in asthmatic and non-asthmatic children and to determine the degree of agreement between the skin prick test and serum specific IgE levels, as well as to establish the relationship between cockroach allergy and total IgE levels. METHODS A case-control study involving 76 asthmatic and ...

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Intradermal Skin Testing in Allergic Rhinitis and Asthma with Negative Skin Prick Tests.

Taking medical history, physical examination, and performing some in vivo and in vitro tests are necessary for the diagnosis of allergy. Skin prick test (SPT) is considered as the standard method and first-line approach for the detection of allergic sensitization. Although mainly SPT is used for the detection of allergic sensitization, intradermal skin test (IDST) may be necessary, especially i...

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ژورنال

عنوان ژورنال: Allergy & Rhinology

سال: 2017

ISSN: 2152-6567,2152-6567

DOI: 10.2500/ar.2017.8.0194